Contraindications and Important Safety Warnings

[3][4][5] Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action

Side Effects of Dapoxetine

Formulated and compounded in pharmacy board-certified facilities. All ingredients thoroughly researched and tested for safety. "What sets Super Strut apart is our exclusive 4-in-1 formula, designed to address both the physical and mental aspects of erectile dysfunction. Each ingredient has been carefully selected and dosed to provide fast-acting, long-lasting results for enhanced performance, confidence, and satisfaction." Simal Patel, MD, Founder & CEO at Strut Health ParoxetineRx is a line of physician-prescribed, compounded oral capsules for premature ejaculation and erectile dysfunction. We mail you a convenient at-home lab test or you can upload your results if you have them. at the postsynaptic cleft, and as a consequence promoting ejaculatory delay.

Question	Answer	Additional Notes
Is dapoxetine safe for long-term use?	Generally safe under medical supervision	Long-term effects still under study
Can women take dapoxetine?	No, it is not indicated for women	Designed specifically for men
What should I do if I miss a dose?	Usually, skip and resume normal schedule	Do not double dose

[6] As a member of the SSRI family, dapoxetine was initially created as an antidepressant.

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However, unlike other SSRIs, dapoxetine is absorbed and eliminated rapidly in the body.

Tolerability and acute toxicity studies

Unlike numbing sprays or topical wipes that reduce sensation, Paroxetine works systemically — regulating serotonin levels in the brain to delay the ejaculatory reflex at its origin. You keep full sensation while lasting longer. All ParoxetineRx formulas include Tadalafil (the active ingredient in Cialis) for erection support. Our Max formulas add Sildenafil and Apomorphine — three ED mechanisms working together for maximum erection support. In clinical studies, Paroxetine produced an approximately 8.8-fold increase in ejaculatory latency over baseline.

STORAGE & DOSAGE:

A 2014 comparative study found that on-demand Paroxetine produced similar improvements to 60mg Dapoxetine. Paroxetine for ejaculation delay, Tadalafil for erection support. Higher-dose Paroxetine for men who need stronger PE support. Paroxetine for PE + three ED ingredients for maximum erection support. Answer a secure health questionnaire from home.

Neurocognitive safety

A U.S.-licensed physician reviews your information to determine if ParoxetineRx is appropriate. Approved medication ships directly to your door in unmarked packaging. Message our medical team anytime through your secure Strut account. Fast-acting formula works in as little as 15 minutes No pills to swallow - convenient dissolvable mint-flavored tablet Comprehensive 4-in-1 approach targets both physical and mental aspects ParoxetineRx is a line of physician-prescribed, compounded oral capsules for premature ejaculation and erectile dysfunction. Our Max formulas add Sildenafil and Apomorphine for enhanced erection support. Its fast-acting property makes it suitable for the treatment of PE, but not as an antidepressant.

• Secreted in breast milk
• Risk to infant is unknown
• Avoid breastfeeding while taking
• Monitor infant for side effects
• Do not use while nursing
• Potential side effects in baby
• Safety not established
• Discontinue drug if nursing
• Consult pediatrician
• Avoid exposure to infant
• Not recommended for breastfeeding mothers
• Seek medical advice

Originally created by Eli Lilly pharmaceutical company, dapoxetine was sold to Johnson & Johnson in 2003 and submitted as a New Drug Application to the US Food and Drug Administration (FDA) for the treatment of PE in 2004.

Transparency document

The results establish your baseline for tracking testosterone improvements and customizing your treatment plan. Health Care Professional-initiated education on U=U significantly improves patients' self-assessed sexual health, irrespective of gender. Further counseling, including mental health assessment and psychosexual therapy, remains the cornerstone of sexual dysfunction treatment for all genders. Primarily oral PDE5 inhibitors (sildenafil, tadalafil, vardenafil)* On-demand use: administer at least 30 minutes before sexual activityContinuous use: Tadalafil 5 mg daily On-demand use: administer at least 30 minutes before sexual activity *Use lower doses with boosted PIs (PI/r or PI/c): sildenafil 25 mg every 48 hours; tadalafil 5 mg as an initial dose, maximum 10 mg every 72 hours; vardenafil 2.5 mg, maximum 2.5 mg every 72 hours Consider behavioral interventions and/or psychosexual counseling, SSRIs, tricyclic antidepressants, clomipramine, and topical anesthetics Use lower doses of clomipramine and other tricyclics with boosted PIs; see Drug-drug interactions between antidepressants and ARVs Dapoxetine, a short-acting SSRI, is the only drug approved for on-demand treatment of premature ejaculation in Europe. Treatment must be maintained, as recurrence is highly likely upon discontinuation Discontinue or switch drugs contributing to delayed ejaculation (antidepressants, antipsychotics, diuretics, antiseizure medications) Treat comorbidities such as hypertension, pelvic nerve injury, or diabetic neuropathy PDE5 inhibitors (e.g., sildenafil — see DDI); benefit in women is generally less than in men Lubricants and/or hormonal therapy (topical or systemic) if pain is related to vaginal dryness Analgesics for pain associated with menstrual symptoms Topical lidocaine, capsaicin, or vestibulectomy for irreversible pain conditions Dapoxetine, sold under the brand name Priligy among others, is a selective serotonin reuptake inhibitor (SSRI) used for the treatment of premature ejaculation (PE) in men ages 18 to 64 years old. [8] Dapoxetine is sold in several European and Asian countries, and in Mexico.

Conclusions and recommendations

ParoxetineRx and ParoxetineRx Plus are 2-ingredient formulas (Paroxetine + Tadalafil) — Plus has a higher Paroxetine dose (40mg vs 20mg) for stronger PE support. Max Double provides a double dose per capsule. Dapoxetine was designed as a fast-acting, on-demand PE treatment (1-2 hours before activity) but is not FDA-approved in the U.S. and has limited availability. Paroxetine is FDA-approved (not for PE, but for depression/anxiety), has decades of safety data, and clinical studies show it produces comparable or stronger ejaculation delay.

Quality Segment

Paroxetine is taken 3-4 hours before activity. A 2014 comparative study found that on-demand Paroxetine and 60mg Dapoxetine produced similar improvements in ejaculatory latency. Meta-analyses have shown Paroxetine sildenafil and dapoxetine produces approximately an 8.8x increase over baseline. Take one capsule 3-4 hours before expected sexual activity, with or without food. Do not take more than one capsule in 24 hours PE effects (Paroxetine) may begin within 3-4 hours.

19. Do you have PICS or EU-GMP compliance?

ED effects (Sildenafil/Tadalafil) may begin within 30-60 minutes. ParoxetineRx is designed for as-needed dosing. Your prescribing physician can help determine the right approach for you. The most common side effects are injection site reactions (redness, mild irritation), joint pain, and mild swelling. Contact your physician if you experience severe swelling, difficulty breathing, or chest tightness. In the US, dapoxetine has been in phase III development.

Study Name	Sample Size	Results	Duration
EAA (Erectile and Anxiety Association)	300 men	Significant delay in ejaculation	12 weeks
International Study Group	500 men	Improvement in control and satisfaction	6 months
Libido & Sexual Satisfaction Research	250 men	No significant adverse effects	8 weeks

In May 2012, US-based Furiex Pharmaceuticals reached an agreement with ALZA Corp and Janssen Pharmaceuticals to market dapoxetine in the United States, Japan,

• Dapoxetine 5mg is a fast-acting medication for on-demand use.
• Its effectiveness depends on correct timing and dosage.
• It may cause dry mouth in some users.
• Sexual arousal is necessary for dapoxetine to work effectively.
• Do not share medication with others, even if similar issues occur.
• Possible interactions with grapefruit juice; check with doctor.
• Always follow the instructions provided by your healthcare provider.

and Canada, while selling the rights to market the drug in Europe, most of Asia, Africa, Latin America, and the Middle East to Menarini.

• Treats premature ejaculation
• Fast-acting SSRI mechanism
• Take 1-3 hours before sex
• Side effects are manageable
• Consult your doctor first
• Not for daily use
• Store at room temperature
• Do not mix with alcohol
• Monitor for side effects
• Effective for many men
• 5mg is a low dose option
• Seek medical advice for use

Randomized, double-blind, placebo-controlled trials have confirmed the efficacy of dapoxetine for the treatment of PE.

• Not approved for use in children
• Safety not established in minors
• Not for use under 18 years
• Dosage unknown for children
• Risk of side effects high
• Off-label use only
• Consult pediatrician
• Do not use in pediatric population
• Safety data lacking
• Risk to developing brain
• Strictly off-label use
• Not recommended for children

[10] Different dosages have different impacts on different types of PE.

Parameter	Description	Typical Values
Absorption Rate	Time to reach peak plasma levels	~1.5 hours
Bioavailability	Percentage of dose reaching systemic circulation	~42%
Half-life	Time for plasma concentration to reduce by half	~20 hours
Metabolism	Liver processing via CYP2D6 and CYP3A4	CYP enzymes involved

Dapoxetine 60 mg significantly improves the mean intravaginal ejaculation latency time (IELT) compared to that of dapoxetine

Satisfaction scores

Maximize your performance with our comprehensive formula. Our exclusive formula addresses all aspects of sexual performance in one convenient rapid dissolve tablet. Active ingredient in Levitra® - Strong and fast acting erectile dysfunction treatment The "Love hormone” for potential libido improvements Just hardcore results at a much lower price. Active ingredient in Cialis® - Provides extended effectiveness for up to 36 hours Primes the brain for arousal and enhanced sensitivity Apomorphine: Primes the brain for arousal and enhanced sensitivity Active ingredient in Cialis® - Provides extended effectiveness for up to 36 hours Active ingredient in Levitra® - Strong and fast acting erectile dysfunction treatment The "Love hormone” for potential libido improvements Just hardcore results at a much lower price. Brief health assessment to customize your treatment plan.

Adverse side effects of 5alpha-reductase inhibitors therapy: persistent diminished libido and erectile dysfunction and depression in a subset of patients

Our physicians develop a personalized solution just dapoxetine sex for you. Our formula was developed by leading physicians and compounding pharmacists with decades of experience in sexual health and performance medicine. Strut is qualified to help you find the right treatment for your needs. We are driven to improve the digital healthcare experience and our team is available to help you throughout the process. Safety Information:All ingredients thoroughly researched and tested for safety. 30 mg in men with lifelong PE, but no difference is seen in men with acquired PE.

5. Call to Action

See the safety information for more detailed potential side effects. Inform your doctor about heart problems, high or low blood pressure, eye conditions, liver or kidney disease, mental health history, seizure history, or if you take MAO inhibitors, nitrates, blood thinners, or other SSRIs. Avoid alcohol (causes low blood pressure and dizziness with Sildenafil/Tadalafil), grapefruit products, nitrate medications, MAO inhibitors, and other ED medications unless directed by your physician. Overdose increases risk of severe nausea, vomiting, dizziness, tremor, or erections lasting 4+ hours (priapism). Store in original container at controlled room temperature (68-77 F).

Publisher's Note

Keep out of reach of children and pets. Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have questions or concerns about your health, please talk to a doctor. Paroxetine is FDA-approved for depression and anxiety; its use for premature ejaculation is off-label. Our ParoxetineRx therapy is overseen by physician and pharmacist-led teams, with input from experienced sexual health specialists.

CAUTION & SCHEDULE:

This treatment is personalized and prescribed for your unique needs. Experience better circulation for more powerful and sustained erections. Feel heightened sensitivity and a quicker, more intense arousal response. Enjoy long-lasting performance with effects that can last up to 36 hours. Feel more confident in the moment, knowing you’re ready for peak performance.