Efficacy and safety of dapoxetine/sildenafil combination tablets in the treatment of men with premature ejaculation and concomitant erectile dysfunction-DAP-SPEED Study
It works by increasing blood flow to the penis and modulating serotonin levels in the brain, enhancing both physical and psychological aspects of male sexual performance. Treats both PE and ED in a single dose Take 1 tablet 1 to 3 hours before sexual activity Swallow whole with water, with or without food Do not exceed 1 dose in 24 hours Use only under medical supervision Common side effects may include: Headache Nausea Dizziness Diarrhea Flushing Nasal congestion Insomnia or agitation Blurred vision Seek immediate medical help if experiencing chest pain, fainting, or prolonged erection (>4 hours).
Who should avoid Priligy?
It works by increasing blood flow to the penis and modulating serotonin levels in the brain, enhancing both physical and psychological aspects of male sexual performance. Treats both PE and ED in a single dose Take 1 tablet 1 to 3 hours before sexual activity Swallow whole with water, with or without food Do not exceed 1 dose in 24 hours Use only under medical supervision Common side effects may include: Headache Nausea Dizziness Diarrhea Flushing Nasal congestion Insomnia or agitation Blurred vision Seek immediate medical help if experiencing chest pain, fainting, or prolonged erection (>4 hours). Not for use in women or individuals under 18 Avoid with nitrate medications or heart conditions Contraindicated in severe liver or kidney impairment Not suitable for individuals with severe depression or psychiatric disorders Do not combine with other ED or SSRI medications Avoid alcohol or recreational drugs (e.g., poppers) sildenafil dapoxetine tablets premature ejaculation and ED combo sexual stamina booster for men fast acting erection and delay pill dapoxetine 30 sildenafil 50 dual action ED and PE treatment PE and ED medicine sildenafil dapoxetine combination delay ejaculation and boost erection men’s performance enhancement tablet Sildenafil and Dapoxetine Tablets are a combination medication designed for the treatment of male sexual health problems, specifically erectile dysfunction (ED) and premature ejaculation (PE). This dual-action formula aims to enhance sexual performance by improving erection quality and prolonging ejaculation time. This medication is primarily used by men facing issues with achieving and maintaining an erection (ED) and experiencing early ejaculation (PE).
-Over Does
It helps in improving sexual satisfaction and performance. Improved Erectile Function: Sildenafil component helps achieve and maintain an erection suitable for sexual activity. Delayed Ejaculation: Dapoxetine helps in delaying ejaculation, providing better control over ejaculation timing. Increased Sexual Confidence: Enhances overall sexual experience and confidence by addressing both ED and PE. While effective, this medication can cause side effects. Not for use in women or individuals under 18 Avoid with nitrate medications or heart conditions Contraindicated in severe liver or kidney impairment Not suitable for individuals with severe depression or psychiatric disorders Do not combine with other ED or SSRI medications Avoid alcohol or recreational drugs (e.g., poppers) sildenafil dapoxetine tablets premature ejaculation and ED combo sexual stamina booster for men fast acting erection and delay pill dapoxetine 30 sildenafil 50 dual action ED and PE treatment PE and ED medicine sildenafil dapoxetine combination delay ejaculation and boost erection men’s performance enhancement tablet Sildenafil and Dapoxetine Tablets are a combination medication designed for the treatment of male sexual health problems, specifically erectile dysfunction (ED) and premature ejaculation (PE). This dual-action formula aims to enhance sexual performance by improving erection quality and prolonging ejaculation time.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Cialis Professional | 20mg | 270 + 6 Pills | 623.07€ 593.40€ | |
| Cialis Generic | 40mg | 180 + 10 Pills | 277.29€ 264.09€ | |
| Priligy Generic Dapoxetine | 60mg | 30 + 6 Pills | 106.65€ 101.57€ | |
| Viagra Generic | 200mg | 120 + 8 Pills | 204.80€ 195.05€ | |
| Cialis Super Active | 20mg | 120 + 16 Pills | 382.15€ 363.95€ | |
| Priligy Generic Dapoxetine | 60mg | 20 + 4 Pills | 77.31€ 73.63€ | |
| Priligy Generic Dapoxetine | 60mg | 60 + 8 Pills | 183.06€ 174.34€ | |
| Viagra Generic | 200mg | 90 + 6 Pills | 170.79€ 162.66€ | |
| Levitra Original | 20mg | 64 + 4 Pills | 298.45€ 284.24€ | |
| Priligy Generic Dapoxetine | 60mg | 120 + 10 Pills | 341.26€ 325.01€ | |
| Priligy Generic Dapoxetine | 60mg | 10 Pills | 47.63€ 45.36€ | |
| Levitra Generic | 10mg | 180 + 10 Pills | 246.74€ 234.99€ | |
| Viagra Soft Tabs | 100mg | 180 + 10 Pills | 314.95€ 299.95€ | |
| Priligy Generic Dapoxetine | 60mg | 90 + 10 Pills | 265.64€ 252.99€ | |
| Priligy Generic Dapoxetine | 60mg | 180 + 10 Pills | 494.76€ 471.20€ | |
| Kamagra Gold | 100 mg | 84 + 6 Pills | 264.44€ 251.85€ |
This medication is primarily used by men facing issues with achieving and maintaining an erection (ED) and experiencing early ejaculation (PE).
- Sildenafil helps improve erectile response in men with ED.
- Dapoxetine may enhance control over ejaculation for men with PE.
- Combining sildenafil and dapoxetine can improve sexual satisfaction.
- Use sildenafil with caution in patients with heart conditions.
- Dapoxetine has a short half-life, suitable for on-demand use.
- Patients should avoid high-fat meals immediately before taking sildenafil.
- Dapoxetine should be taken with a full glass of water.
- Both drugs are contraindicated in patients with certain heart problems.
It helps in improving sexual satisfaction and performance.
- Sildenafil can cause a drop in blood pressure in some users.
- Dapoxetine's adverse effects are usually mild and transient.
- Patients on medication for heart disease should consult a doctor first.
- Sexual activity itself can pose risks for some health conditions.
- Combining sildenafil with other ED medications is not recommended.
- Dapoxetine may interact with other serotonergic drugs.
- Use caution when operating machinery after taking these drugs.
- Always inform your doctor about other medications being used.
Improved Erectile Function: Sildenafil component helps achieve and maintain an erection suitable for sexual activity. Delayed Ejaculation: Dapoxetine helps in delaying ejaculation, providing better control over ejaculation timing. Increased Sexual Confidence: Enhances overall sexual experience and confidence by addressing both ED and PE.
| Region | Typical Price Range (USD) | Availability | Notes |
|---|---|---|---|
| North America | 20-50 per pack | Widely available through pharmacies | Prescription often required |
| Europe | 15-45 per pack | Over-the-counter and prescription options | Varies by country |
| Asia | 10-30 per pack | Readily accessible in many markets | Often lower cost |
| Online Pharmacies | Price varies | Ensure reputable sources | Beware of counterfeit products |
While effective, this medication can cause side effects. Common side effects include headache, nausea, dizziness, and flushing. Rare but more serious side effects may include vision changes, sudden hearing loss, and prolonged erections. If you experience severe side effects, seek immediate medical attention. Take this medication orally, with or without food, approximately 1 hour before sexual activity, or as directed by your healthcare provider. Do not take more than once daily. The dosage is based on your medical condition, response to treatment, and other medications you may be taking.
| Focus Area | Description | Expected Outcomes |
|---|---|---|
| New Delivery Systems | Development of fast-dissolving or transdermal patches | Improved compliance and onset time |
| Combination Therapies | Combining sildenafil with other agents for enhanced effects | Broader treatment spectrum |
| Reduced Side Effects | Formulations aiming to minimize adverse reactions | Better patient tolerability |
| Personalized Medicine | Genetic-based dosing and predictions | More precise and safe therapy |
Sildenafil works by increasing blood flow to the penis to help a man get and keep an erection.
Additional information
However, sildenafil tablets may be taken anywhere from 30 minutes to 4 hours before sexual activity ( 2.1) Based on effectiveness and toleration, may increase to a maximum of 100 mg or decrease to 25 mg ( 2.1) Maximum recommended dosing frequency is once per day ( 2.1) Tablets: 25 mg, 50 mg, 100 mg ( 3) Administration of sildenafil tablets to patients using nitric oxide donors, such as organic nitrates or organic nitrites in any form. Sildenafil tablets was shown to potentiate the hypotensive effect of nitrates ( 4.1, 7.1, 12.2) Known hypersensitivity to sildenafil or any component of tablet ( 4.2) Administration with guanylate cyclase (GC) stimulators, such as riociguat ( 4.3) Patients should not use sildenafil tablets if sexual activity is inadvisable due to cardiovascular status ( 5.1) Patients should seek emergency treatment if an erection lasts >4 hours. Use sildenafil tablets with caution in patients predisposed to priapism ( 5.2) Patients should stop sildenafil tablets and seek medical care if a sudden loss of vision occurs in one or both eyes, which could be a sign of non arteritic anterior ischemic optic neuropathy (NAION). Patients should stop sildenafil tablets and seek prompt medical attention in the event of sudden decrease or loss of hearing ( 5.4) Caution is advised when sildenafil tablets is co-administered with alpha-blockers or anti- hypertensives. Concomitant use may lead to hypotension ( 5.5) Decreased blood pressure, syncope, and prolonged erection may occur at higher sildenafil exposures.
How sildenafil is used
Decrease in sildenafil tablets dosage is recommended ( 2.4, 5.6) Most common adverse reactions (≥ 2%) include headache, flushing, dyspepsia, abnormal vision,nasal congestion, back pain, myalgia, nausea, dizziness and rash ( 6.1) To report SUSPECTED ADVERSE REACTIONS, contact Advagen Pharma Ltd, at 866-488-0312 or FDA at 1-800-FDA-1088 or Sildenafil can potentiate the hypotensive effects of nitrates, alpha blockers, and anti- hypertensives ( 4.1, 5.5, 7.1, 7.2, 7.3, 12.2) With concomitant use of alpha blockers, initiate sildenafil at 25 mg dose ( 2.3) CYP3A4 inhibitors (e.g., ritonavir, ketoconazole, itraconazole, erythromycin): Increase sildenafil exposure ( 2.4, 7.4, 12.3) See 17 for PATIENT COUNSELING INFORMATION and FDA-approved patient labeling. Dapoxetine, on the other hand, works by delaying the ejaculation process. Together, they improve both erection quality and ejaculation time. Store the tablets at room temperature, away from light and moisture.
5.8 Effects on Bleeding
Product Sertraline Tablets BP 25 mg
Keep all medications away from children and pets. Consult your healthcare provider before taking this medication, especially if you have a history of heart disease, high or low blood pressure, liver or kidney disease, dehydration, or are taking medications for depression. Avoid using this medication with recreational drugs containing nitrates or ‘poppers’.
| Ingredient | Quantity per Tablet | Function | Notes |
|---|---|---|---|
| Sildenafil Citrate | 100 mg | Erectile dysfunction treatment | Active ingredient |
| Dapoxetine Hydrochloride | 60 mg | Premature ejaculation relief | Active ingredient |
| Microcrystalline Cellulose | 50 mg | Binder | Inactive excipient |
| Magnesium Stearate | 5 mg | Lubricant | Inactive excipient |
| Lactose Monohydrate | 20 mg | Filler | Inactive excipient |
Limit or avoid alcohol consumption, as it tadalafil with dapoxetine tablets can increase some of the side effects. Sildenafil and Dapoxetine Tablets by JoinHub Pharma, exemplifies pharmaceutical excellence, meticulously crafted to exceed industry standards.
Safety and tolerability
Approval: 1998RECENT MAJOR CHANGESWarnings and Precautions, Effects on the Eye ( 5.3)INDICATIONS AND USAGESildenafil tablets are phosphodiesterase-5 (PDE5) inhibitor indicated for the treatment of erectile dysfunction (ED) ( 1)DOSAGE AND ADMINISTRATIONFor most patients, the recommended dose is 50 mg taken, as needed, approximately 1 hour before sexual activity. However, sildenafil tablets may be taken anywhere from 30 minutes to 4 hours before sexual activity ( 2.1)Based on effectiveness and toleration, may increase to a maximum of 100 mg or decrease to 25 mg ( 2.1)Maximum recommended dosing frequency is once per day ( 2.1)DOSAGE FORMS AND STRENGTHSTablets: 25 mg, 50 mg, 100 mg ( 3)CONTRAINDICATIONSAdministration of sildenafil tablets to patients using nitric oxide donors, such as organic nitrates or organic nitrites in any form. Sildenafil tablets was shown to potentiate the hypotensive effect of nitrates ( 4.1, 7.1, 12.2)Known hypersensitivity to sildenafil or any component of tablet ( 4.2)Administration with guanylate cyclase (GC) stimulators, such as riociguat ( 4.3)WARNINGS AND PRECAUTIONSPatients should not use sildenafil tablets if sexual activity is inadvisable due to cardiovascular status ( 5.1)Patients should seek emergency treatment if an erection lasts >4 hours. Use sildenafil tablets with caution in patients predisposed to priapism ( 5.2)Patients should stop sildenafil tablets and seek medical care if a sudden loss of vision occurs in one or both eyes, which could be a sign of non arteritic anterior ischemic optic neuropathy (NAION). Sildenafil tablets should be used with caution, and only when the anticipated benefits outweigh the risks, in patients with a history of NAION.
Dapoxetine sildenafil
Patients with a "crowded" optic disc may also be at an increased risk of NAION. ( 5.3)Patients should stop sildenafil tablets and seek prompt medical attention in the event of sudden decrease or loss of hearing ( 5.4)Caution is advised when sildenafil tablets is co-administered with alpha-blockers or anti- hypertensives. Concomitant use may lead to hypotension ( 5.5)Decreased blood pressure, syncope, and prolonged erection may occur at higher sildenafil exposures. In patients taking strong CYP inhibitors, such as ritonavir, sildenafil exposure is increased. Decrease in sildenafil tablets dosage is recommended ( 2.4, 5.6)ADVERSE REACTIONSMost common adverse reactions (≥ 2%) include headache, flushing, dyspepsia, abnormal vision,nasal congestion, back pain, myalgia, nausea, dizziness and rash ( 6.1)To report SUSPECTED ADVERSE REACTIONS, contact Advagen Pharma Ltd, at 866-488-0312 or FDA at 1-800-FDA-1088 or INTERACTIONSSildenafil can potentiate the hypotensive effects of nitrates, alpha blockers, and anti- hypertensives ( 4.1, 5.5, 7.1, 7.2, 7.3, 12.2)With concomitant use of alpha blockers, initiate sildenafil at 25 mg dose ( 2.3)CYP3A4 inhibitors (e.g., ritonavir, ketoconazole, itraconazole, erythromycin): Increase sildenafil exposure ( 2.4, 7.4, 12.3)USE IN SPECIFIC POPULATIONSSee 17 for PATIENT COUNSELING INFORMATION and FDA-approved patient labeling.Revised: 1/2026 Warnings and Precautions, Effects on the Eye ( 5.3) Sildenafil tablets are phosphodiesterase-5 (PDE5) inhibitor indicated for the treatment of erectile dysfunction (ED) ( 1) For most patients, the recommended dose is 50 mg taken, as needed, approximately 1 hour before sexual activity. Renowned for our unwavering commitment to quality, as WHO-GMP and EU-GMP Manufacturers, suppliers, and exporters, we assure unparalleled efficacy and reliability. For further information on Sildenafil and Dapoxetine Tablets, please contact us via email at info@joinhubpharma.com or call us at +91-9724725604. NDC Code(s): 72888-015-05, 72888-015-30, 72888-016-00, 72888-016-01, view more72888-016-30, 72888-017-00, 72888-017-01, 72888-017-30 If you are a consumer or patient please visit this version. HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use SILDENAFIL TABLETS safely and effectively. See full prescribing information for SILDENAFIL TABLETSSILDENAFIL tablets, for oral useInitial U.S. Approval: 1998RECENT MAJOR CHANGESWarnings and Precautions, Effects on the Eye ( 5.3)INDICATIONS AND USAGESildenafil tablets are phosphodiesterase-5 (PDE5) inhibitor indicated for the treatment of erectile dysfunction (ED) ( 1)DOSAGE AND ADMINISTRATIONFor most patients, the recommended dose is 50 mg taken, as needed, approximately 1 hour before sexual activity. However, sildenafil tablets may be taken anywhere from 30 minutes to 4 hours before sexual activity ( 2.1)Based on effectiveness and toleration, may increase to a maximum of 100 mg or decrease to 25 mg ( 2.1)Maximum recommended dosing frequency is once per day ( 2.1)DOSAGE FORMS AND STRENGTHSTablets: 25 mg, 50 mg, 100 mg ( 3)CONTRAINDICATIONSAdministration of sildenafil tablets to patients using nitric oxide donors, such as organic nitrates or organic nitrites in any form. Sildenafil tablets was shown to potentiate the hypotensive effect of nitrates ( 4.1, 7.1, 12.2)Known hypersensitivity to sildenafil or any component of tablet ( 4.2)Administration with guanylate cyclase (GC) stimulators, such as riociguat ( 4.3)WARNINGS AND PRECAUTIONSPatients should not use sildenafil tablets if sexual activity is inadvisable due to cardiovascular status ( 5.1)Patients should seek emergency treatment if an erection lasts >4 hours.
4.2 Hypersensitivity Reactions
Molecular Weight
Use sildenafil tablets with caution in patients predisposed to priapism ( 5.2)Patients should stop sildenafil tablets and seek medical care if a sudden loss of vision occurs in one or both eyes, which could be a sign of non arteritic anterior ischemic optic neuropathy (NAION).
- Sildenafil is used to treat erectile dysfunction in men.
- Dapoxetine is primarily prescribed for premature ejaculation.
- Sildenafil increases blood flow to the penis during arousal.
- Dapoxetine works by delaying serotonin reuptake, extending ejaculation time.
- Both medications require a prescription from a healthcare provider.
- Sildenafil usually takes about 30-60 minutes to work.
- Dapoxetine is typically taken 1-3 hours before sexual activity.
- Combining sildenafil and dapoxetine should only be done under medical guidance.
Sildenafil tablets should be used with caution, and only when the anticipated benefits outweigh the risks, in patients with a history of NAION. Patients with a "crowded" optic disc may also be at an increased risk of NAION. ( 5.3)Patients should stop sildenafil tablets and seek prompt medical attention in the event of sudden decrease or loss of hearing ( 5.4)Caution is advised when sildenafil tablets is co-administered with alpha-blockers or anti- hypertensives. Concomitant use may lead to hypotension ( 5.5)Decreased blood pressure, syncope, and prolonged erection may occur at higher sildenafil exposures.
Usage Information
Common side effects include headache, nausea, dizziness, and flushing. Rare but more serious side effects may include vision changes, sudden hearing loss, and prolonged erections. If you experience severe side effects, seek immediate medical attention. Take this medication orally, with or without food, approximately 1 hour before sexual activity, or as directed by your healthcare provider. Do not take more than once daily.
Neurocognitive safety
The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Sildenafil works by increasing blood flow to the penis to help a man get and keep an erection. Dapoxetine, on the other hand, works by delaying the ejaculation process. Together, they improve both erection quality and ejaculation time. Store the tablets at room temperature, away from light and moisture. In patients taking strong CYP inhibitors, such as ritonavir, sildenafil exposure is increased.
How to Do Sildenafil Citrate and Dapoxetine Tablets Work
Keep all medications away from children and pets. Consult your healthcare provider before taking this medication, especially if you have a history of heart disease, high or low blood pressure, liver or kidney disease, dehydration, or are taking medications for depression. Avoid using this medication with recreational drugs containing nitrates or ‘poppers’. Limit or avoid alcohol consumption, as it tadalafil with dapoxetine tablets can increase some of the side effects. Sildenafil and Dapoxetine Tablets by JoinHub Pharma, exemplifies pharmaceutical excellence, meticulously crafted to exceed industry standards.
Premature ejaculation
Renowned for our unwavering commitment to quality, as WHO-GMP and EU-GMP Manufacturers, suppliers, and exporters, we assure unparalleled efficacy and reliability. For further information on Sildenafil and Dapoxetine Tablets, please contact us via email at info@joinhubpharma.com or call us at +91-9724725604. NDC Code(s): 72888-015-05, 72888-015-30, 72888-016-00, 72888-016-01, view more72888-016-30, 72888-017-00, 72888-017-01, 72888-017-30 If you are a consumer or patient please visit this version. HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use SILDENAFIL TABLETS safely and effectively. See full prescribing information for SILDENAFIL TABLETSSILDENAFIL tablets, for oral useInitial U.S. Decrease in sildenafil tablets dosage is recommended ( 2.4, 5.6)ADVERSE REACTIONSMost common adverse reactions (≥ 2%) include headache, flushing, dyspepsia, abnormal vision,nasal congestion, back pain, myalgia, nausea, dizziness and rash ( 6.1)To report SUSPECTED ADVERSE REACTIONS, contact Advagen Pharma Ltd, at 866-488-0312 or FDA at 1-800-FDA-1088 or INTERACTIONSSildenafil can potentiate the hypotensive effects of nitrates, alpha blockers, and anti- hypertensives ( 4.1, 5.5, 7.1, 7.2, 7.3, 12.2)With concomitant use of alpha blockers, initiate sildenafil at 25 mg dose ( 2.3)CYP3A4 inhibitors (e.g., ritonavir, ketoconazole, itraconazole, erythromycin): Increase sildenafil exposure ( 2.4, 7.4, 12.3)USE IN SPECIFIC POPULATIONSSee 17 for PATIENT COUNSELING INFORMATION and FDA-approved patient labeling.Revised: 1/2026 Warnings and Precautions, Effects on the Eye ( 5.3) Sildenafil tablets are phosphodiesterase-5 (PDE5) inhibitor indicated for the treatment of erectile dysfunction (ED) ( 1) For most patients, the recommended dose is 50 mg taken, as needed, approximately 1 hour before sexual activity. However, sildenafil tablets may be taken anywhere from 30 minutes to 4 hours before sexual activity ( 2.1) Based on effectiveness and toleration, may increase to a maximum of 100 mg or decrease to 25 mg ( 2.1) Maximum recommended dosing frequency is once per day ( 2.1) Tablets: 25 mg, 50 mg, 100 mg ( 3) Administration of sildenafil tablets to patients using nitric oxide donors, such as organic nitrates or organic nitrites in any form.
- Sildenafil can be combined with lifestyle changes for better results.
- Dapoxetine helps subjects gain better control during sexual activity.
- Use caution in hot weather as both drugs can cause dehydration.
- Patients should avoid grapefruit or high-fat foods around intake time.
- Sildenafil has been studied extensively for safety and efficacy.
- Dapoxetine's rapid onset makes it convenient for planned activity.
- These medications are not substitutes for safe sexual practices.
- Always follow the prescribed dosage and timing instructions.
Sildenafil tablets was shown to potentiate the hypotensive effect of nitrates ( 4.1, 7.1, 12.2) Known hypersensitivity to sildenafil or any component of tablet ( 4.2) Administration with guanylate cyclase (GC) stimulators, such as riociguat ( 4.3) Patients should not use sildenafil tablets if sexual activity is inadvisable due to cardiovascular status ( 5.1) Patients should seek emergency treatment if an erection lasts >4 hours. Use sildenafil tablets with caution in patients predisposed to priapism ( 5.2) Patients should stop sildenafil tablets and seek medical care if a sudden loss of vision occurs in one or both eyes, which could be a sign of non arteritic anterior ischemic optic neuropathy (NAION). Patients should stop sildenafil tablets and seek prompt medical attention in the event of sudden decrease or loss of hearing ( 5.4) Caution is advised when sildenafil tablets is co-administered with alpha-blockers or anti- hypertensives. Concomitant use may lead to hypotension ( 5.5) Decreased blood pressure, syncope, and prolonged erection may occur at higher sildenafil exposures. Decrease in sildenafil tablets dosage is recommended ( 2.4, 5.6) Most common adverse reactions (≥ 2%) include headache, flushing, dyspepsia, abnormal vision,nasal congestion, back pain, myalgia, nausea, dizziness and rash ( 6.1) To report SUSPECTED ADVERSE REACTIONS, contact Advagen Pharma Ltd, at 866-488-0312 or FDA at 1-800-FDA-1088 or Sildenafil can potentiate the hypotensive effects of nitrates, alpha blockers, and anti- hypertensives ( 4.1, 5.5, 7.1, 7.2, 7.3, 12.2) With concomitant use of alpha blockers, initiate sildenafil at 25 mg dose ( 2.3) CYP3A4 inhibitors (e.g., ritonavir, ketoconazole, itraconazole, erythromycin): Increase sildenafil exposure ( 2.4, 7.4, 12.3) See 17 for PATIENT COUNSELING INFORMATION and FDA-approved patient labeling.
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