WARNINGS AND PRECAUTIONS
CrCl<30mL/min or hemodialysis: not recommended.
| Ingredient | Quantity per Tablet | Function | Notes |
|---|---|---|---|
| Tadalafil | 10 mg | Active pharmaceutical ingredient | Main component for efficacy |
| Lactose | 50 mg | Filler | For tablet bulk |
| Microcrystalline Cellulose | 20 mg | Binder | Helps hold tablet together |
| Magnesium Stearate | 2 mg | Lubricant | Prevents sticking during compression |
| Croscarmellose Sodium | 5 mg | Disintegrant | Ensures tablet dissolves |
Both ED Uses: Concomitant α-blockers: use lowest recommended dose (see full labeling). ED/BPH: 5mg once daily (taken at same time each day). Renal impairment: CrCl 30–50mL/min: initially 2.5mg; may increase to 5mg/day; CrCl <30mL/min or hemodialysis: not recommended. For BPH: concomitant α-blockers: not recommended. Since its FDA approval in 2003, Cialis medication has become one of the most recognized names in the treatment of erectile dysfunction (ED). Known for its long duration of action (up to 36 hours) and the option for daily dosing, Cialis quickly became a preferred choice for millions of men worldwide.
| Side Effect | Frequency | Severity | Recommended Action |
|---|---|---|---|
| Headache | Common | Mild | Usually temporary; OTC pain relief can help |
| Dyspepsia (Indigestion) | Common | Mild | Dietary adjustments or antacids |
| Muscle Aches | Less common | Mild | Rest or analgesics |
| Flushing | Common | Mild | Cooling measures; usually transient |
| Vision Changes | Rare | Moderate | Seek medical advice if sudden vision disturbance occurs |
Beyond ED, it’s also approved for managing benign prostatic hyperplasia (BPH) and, under a different brand name, pulmonary arterial hypertension.
How Cialis (tadalafil) works?
So I’m on them until things normalize unless the Dr says to stop It does help me my erections, but since it's only 5mg daily my doctor told me to take 4 tablets (3 extra tablets for a total of 20mg) on the days I want to try having sex. Even when I take 20mg I'm only 65% firmness on a good day, but hopefully it'll keep improving. If not I'll eventually discuss with my doctor what's next to try. The increased blood flow protects the nerves which wither without blood supply. The 5mg may give you a twinge, but isn't enough and isn't intended to facilitate function.
The Bottom Line
You might take it during radiation and during the several weeks after that radiation is thought to continue to affect cells. Mark Cuban sells a 90-day supply of 5mg Tadalafil (generic for Cialis) for $10.40 by mail order. Tabs 2.5mg—2×15 (blisters); 5mg—30, 2×15 (blisters); 10mg, 20mg—30 If concomitant with finasteride to initiate BPH treatment, such use is recommended for up to 26 weeks. ≥18yrs: 5mg once daily (taken at same time each day). Renal impairment: CrCl 30–50mL/min: initially 2.5mg; may increase to 5mg/day. Its success in clinical use, along with favorable tolerability, led to widespread demand and, eventually, generic competition.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Cialis Generic | 20mg | 180 + 10 Pills | 254.09€ 241.99€ | |
| Cialis Generic | 20mg | 90 + 6 Pills | 154.71€ 147.34€ | |
| Cialis Professional | 20mg | 60 + 2 Pills | 183.83€ 175.08€ | |
| Cialis Generic | 2.5mg | 270 + 10 Pills | 199.64€ 190.13€ | |
| Cialis Super Active | 20mg | 270 + 30 Pills | 661.49€ 629.99€ | |
| Cialis Professional | 40mg | 30 Pills | 148.94€ 141.85€ | |
| Cialis Generic | 60mg | 30 + 2 Pills | 85.33€ 81.27€ | |
| Cialis Super Active | 20mg | 20 + 4 Pills | 92.35€ 87.95€ | |
| Cialis Professional | 20mg | 120 + 4 Pills | 291.68€ 277.79€ | |
| Cialis Professional | 40mg | 270 + 6 Pills | 898.37€ 855.59€ | |
| Cialis Super Active | 20mg | 180 + 20 Pills | 521.59€ 496.75€ | |
| Cialis Generic | 2.5mg | 180 + 10 Pills | 154.86€ 147.49€ | |
| Cialis Generic | 5mg | 10 Pills | 29.39€ 27.99€ |
With the expiration of the Cialis patent in 2018, a new chapter began.
What should I know about storage and disposal of this medication?
CrCl <30mL/min or hemodialysis: not recommended. Concomitant potent CYP3A4 inhibitors (See Interactions): max 2.5mg/day. Cardiovascular disease (eg, MI within 90 days, unstable angina or angina during intercourse, NYHA Class 2 or greater HF or stroke within 6 months; hypotension [<90/50mmHg], uncontrolled hypertension or arrhythmias, severely impaired autonomic BP regulation, LV outflow obstruction), severe hepatic impairment, hereditary degenerative retinal disorders including retinitis pigmentosa: not recommended. Underlying non-arteritic anterior ischemic optic neuropathy risk factors. Advise patients to discontinue if sudden vision or hearing loss occurs.
What is tadalafil used for?
Patients for whom sexual activity is inadvisable or contraindicated. Hypotension with nitrates, GC stimulators, other antihypertensives, alcohol (≥5 units). Potentiated by CYP3A4 inhibitors (eg, ketoconazole, itraconazole, protease inhibitors, erythromycin, grapefruit juice). Concomitant α-blockers: not recommended; discontinue at least 1 day prior to therapy. Concomitant other erectile dysfunction treatments: not recommended. Generic Cialis, sold under the name tadalafil, entered the market at a significantly lower cost while maintaining the same therapeutic efficacy. Many patients now ask: What is Cialis used for today? Is there any difference between Cialis and tadalafil? This article provides a comprehensive overview of Cialis and its generics, from active ingredients and approved indications to formulation types and appropriate use. Whether you’re considering your first prescription or switching to a generic, understanding the distinctions between brand-name Cialis and generic tadalafil is essential for making informed treatment decisions.
17.9 Sexually Transmitted Disease
Ongoing monitoring of efficacy, tolerability, blood pressure, and interactions is appropriate, especially when comorbidities or new medications are introduced. Disclaimer: This material is informational and does not replace individual medical advice. Decisions about initiating, adjusting, or discontinuing therapy should be made with a qualified clinician, particularly in the presence of cardiovascular disease, visual or auditory symptoms, or medications that interact with tadalafil. My physio recommended 5mg of Cialis per day.Apparently it assists with repairing/preventing scar tissue from forming (and helps with incontinence?) How do I know it's doing any good & how long will I need to take them for?28 Cialis tablets is $200 but I was told that the generic tabs did the same thing. $50 for 28.So I'm on them.For how long & what does it even do?
1. They Look Different
Go to the Prostate Cancer Support Group. I’m on them as they help with my flow of urine. In Florida, I purchased 30 generic tabs for $29 I use free Goodrx.com coupons from the internet and get mine in Nevada for just under $20 for 30 5mg tablets (generic). But the deals seem to change month by month, so I always check before I get a prescription so I know where I want the provider to send the prescription. Once I have a prescription, so far multiple pharmacies have honored that same price for the refills until the prescription runs out as long as it's not some 1 month special rate. At the core of all Cialis products is the active ingredient tadalafil, a long-acting phosphodiesterase type 5 (PDE5) inhibitor. This compound enhances blood flow by relaxing smooth muscle in the blood vessels, particularly in the corpus cavernosum of the penis, the prostate, and the pulmonary vasculature.
Warnings & Precautions
Headache, dyspepsia, back pain, myalgia, nasal congestion, flushing, limb pain; sudden vision or hearing cialis sublingual loss, cardiovascular effects; rare: priapism, prolonged erection. Tabs 2.5mg—2×15 (blisters); 5mg—30, 2×15 (blisters); 10mg, 20mg—30 Treatment of ED and signs/symptoms of benign prostatic hyperplasia (BPH). If concomitant with finasteride to initiate BPH treatment, such use is recommended for up to 26 weeks. ≥18yrs: ED: As Needed Use: Initially 10mg (taken before sexual activity), range: 5–20mg. Max dosing: once daily; effect may last ≤36hrs.
Take as part of a healthy lifestyle
Renal impairment: CrCl 30–50mL/min: initially 5mg/day; max 10mg per 48hrs; CrCl <30mL/min or hemodialysis: max 5mg per 72hrs. Mild-to-moderate hepatic impairment: max 10mg/day. Concomitant potent CYP3A4 inhibitors (See Interactions): max 10mg per 72hrs. Once-Daily Use: Initially 2.5mg (taken at same time each day); may increase to 5mg/day. Concomitant potent CYP3A4 inhibitors (See Interactions): max 2.5mg. Tadalafil works by increasing levels of cyclic guanosine monophosphate (cGMP), a molecule involved in vasodilation.
- [Part of a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors.]
- [Other PDE5 inhibitors include sildenafil (Viagra) and vardenafil (Levitra).]
- [Tadalafil is distinguished by its significantly longer duration of action.]
- [Choice of medication depends on individual response, side effects, and lifestyle.]
- [Do not take tadalafil concurrently with other PDE5 inhibitors.]
Because of this mechanism, Cialis medication is effective not only for sexual health but also for certain urinary and cardiovascular conditions. The drug is FDA-approved for three primary indications: Erectile dysfunction (ED) – Taken either on demand or daily to improve the ability to achieve and maintain an erection in response to sexual stimulation. Benign prostatic hyperplasia (BPH) – Used as a daily therapy to relieve urinary symptoms such as frequency, urgency, and weak stream caused by prostate enlargement. Pulmonary arterial hypertension (PAH) – Though not under the Cialis brand, tadalafil is also marketed as Adcirca to treat PAH by improving exercise capacity through pulmonary vasodilation. It’s important to clarify that Cialis is not approved for use in women or children. While there is ongoing research into tadalafil’s effects in female populations, such as for pulmonary hypertension and overactive bladder, the drug is not indicated for increasing libido or treating sexual dysfunction in women. There are other agents, such as flibanserin or bremelanotide, which are specifically studied for female sexual interest/arousal disorder.
- Cialis 10mg tablets should be stored in a cool, dry environment.
- Protect the medication from direct sunlight and moisture.
- Proper storage ensures medication stability and safety.
- Keep Cialis out of sight and reach of children and pets.
- Do not use expired Cialis tablets; dispose of them safely.
- Store away from heat sources to prevent degradation.
- Use original packaging to keep track of medication.
- If you experience any storage issues, consult your pharmacist.
- Keep a record of medication expiry dates for safety.
- Avoid storing Cialis in the bathroom due to humidity.
- Use a designated medication container for safe storage.
In all its approved forms, including generic Cialis (tadalafil), this medication offers proven, targeted effects for vascular-related dysfunction, making it a cornerstone in both urology and cardiopulmonary care. Researchers continue to explore the broader therapeutic potential of PDE5 inhibitors beyond their established indications.
Overdose/Missed Dose
Also, although I have insurance, I don't use the insurance and just pay cash with the Goodrx coupon. Ditto for sildenafil, which I was using, but my doctor switched me to tadalafil after my recent NS RALP. I'm not a medical professional, but I think part of the reason for the switch is sildenafil clears out of the body in about 8 hours while tadalafil last until the next daily dose. I do think they're helping me with a generally increased blood flow to the penis. Since I can get it for less than $20 a month and I don't have any negative side effects from taking it, I'm going to continue taking it until my doctor tells me it's no longer indicated.
Limitations of Use
However, since I was on sildenafil before my RALP, I suspect that may be never. My urologist had prescribed them about two years ago for slow urine flow. Then my RO said to continue to take them as my urination became even more difficult due to the 40 sessions of radiation. I continue to take them along with flomax. One day I didn’t take them and I immediately had more difficulty urinating. In this evolving landscape, tadalafil has shown promise in several novel clinical applications. Recent studies have investigated its effects on cognitive function in schizophrenia, vascular health in small vessel disease, and even potential benefits for inflammatory conditions. These emerging research avenues highlight the drug’s multifaceted biological activity and suggest new therapeutic possibilities that extend well beyond its original urological indications. Clock-Tuning with cGMP: Could Tadalafil Influence Circadian Rhythm and Psychiatric Sleep Disturbance?
| Usage | Indication | Typical Dosage | Onset of Action | Duration of Effect |
|---|---|---|---|---|
| Erectile Dysfunction | Helps achieve/maintain erection | 10 mg before activity | 30-60 minutes | Up to 36 hours |
| Benign Prostatic Hyperplasia | Symptom relief | 10 mg daily | Varies | Varies |
| Pulmonary Hypertension | Improves exercise capacity | 40 mg/day (not typical for Cialis) | Variable | Up to 24 hours |
Mind over Libido: Using Tadalafil to Counter SSRI-Induced Sexual Dysfunction and Protect Treatment Adherence Emerging Evidence for PDE5 Inhibition in Dementia Prevention The term Cialis refers to the original, brand-name version of tadalafil, developed by ICOS and marketed by Eli Lilly.